EUR 160-320 per nightThannenkirch
Three-star spa hotel in the wooded village of Thannenkirch between Strasbourg and Colmar, 10 km from the Route des Vins, with an indoor pool, sauna and hammam.
The list: Cellar weighted to grower Alsace; concierge bookings at Ribeauville, Bergheim and Rorschwihr cellars
EUR 320-700 per nightKaysersberg
Five-star Relais et Chateaux hotel in 18th-century Kaysersberg, home of Olivier Nasti's two-Michelin-star Table d'Olivier Nasti, an infinity pool spa and a winstub on the Route des Vins.
The list: Two-Michelin-star Table d'Olivier Nasti pairings; winstub with Alsace by-the-glass; concierge cellar visits along the Route des Vins
EUR 280-650 per nightColmar old town
Five-star Relais et Chateaux hotel inside the 1609 Renaissance Maison des Tetes in Colmar, home to chef Eric Girardin's one-Michelin-star restaurant and a historic Alsatian brasserie.
The list: Restaurant Girardin Michelin-star tasting menu; Brasserie Historique with Alsace by-the-glass; concierge-arranged cellar visits
EUR 200-380 per nightColmar old town
Boutique 14-key hotel in a former 19th-century pharmacy on Rue des Augustins, steps from Petite Venise and Musee Unterlinden. Curated Alsace wine fridge and concierge tasting bookings.
The list: In-room curated Alsace minibar; concierge bookings at Wolfberger, Hugel and Trimbach cellars
EUR 180-380 per nightBergheim
Suite hotel on Bergheim's Grand Rue in a 16th-century property with a spa, restaurant and winstub. Hand-walking distance to the Altenberg Grand Cru and Domaine Marcel Deiss cellar.
The list: Hotel restaurant and winstub pour grower Bergheim Alsace; concierge-arranged tastings at Domaine Marcel Deiss and Sylvie Spielmann
EUR 180-420 per nightObernai
Four-star HappyCulture hotel and spa in medieval Obernai, set in 17th-century mansions with a winstub, gastronomic restaurant Le Jardin des Remparts and a deep Alsace cellar.
The list: Le Jardin des Remparts and winstub Cour d'Alsace pour grower Alsace lists; sommelier-led tastings inside the cellar